BDBM66065 5-fluoranyl-7-nitro-quinolin-8-ol::5-fluoro-7-nitro-8-quinolinol::5-fluoro-7-nitro-quinolin-8-ol::5-fluoro-7-nitroquinolin-8-ol::MLS000736929::SMR000528432::cid_260644

SMILES Oc1c(cc(F)c2cccnc12)[N+]([O-])=O

InChI Key InChIKey=WJOHCSADJQUMCX-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 66065   

TargetVacuolar aminopeptidase 1(Baker's yeast)
Nmmlsc

Curated by PubChem BioAssay
LigandPNGBDBM66065(5-fluoro-7-nitroquinolin-8-ol | MLS000736929 | SMR...)
Affinity DataEC50:  1.19E+3nMAssay Description:University of New Mexico Assay Overview: Assay Support: 1R03 MH086450-01 Project Title: Chemical Screen of TOR pathway GFP fusion proteins in S. ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetSentrin-specific protease 8(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM66065(5-fluoro-7-nitroquinolin-8-ol | MLS000736929 | SMR...)
Affinity DataIC50: 1.20E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetSentrin-specific protease 8(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM66065(5-fluoro-7-nitroquinolin-8-ol | MLS000736929 | SMR...)
Affinity DataIC50: 1.20E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetIndoleamine 2,3-dioxygenase 1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM66065(5-fluoro-7-nitroquinolin-8-ol | MLS000736929 | SMR...)
Affinity DataIC50: 1.46E+4nMAssay Description:Inhibition of recombinant human IDO1 expressed in Escherichia coli EC538 assessed as reduction in N-formylkynurenine formation using L-tryptophan as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed
TargetTryptophan 2,3-dioxygenase(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM66065(5-fluoro-7-nitroquinolin-8-ol | MLS000736929 | SMR...)
Affinity DataIC50: 3.02E+4nMAssay Description:Inhibition of recombinant human TDO2 expressed in Escherichia coli BL21 (DE3) assessed as reduction in N-formylkynurenine formation using L-tryptopha...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2022
Entry Details Article
PubMed