BDBM660326 US20240092799, Compound IIb

SMILES Cc1cc(Nc2cc(N)ncn2)c(=O)n2c1C(=O)NC21C[C@@H]2CC[C@H]1C2

InChI Key InChIKey=OROGTVJVVOAHJX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 660326   

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Human)
Hepagene Therapeutics (Hk

US Patent
LigandPNGBDBM660326(US20240092799, Compound IIb)
Affinity DataIC50: 5.5nMAssay Description:This protocol establishes the binding assays for MNK1 and MNK2 using ADP-Glo assay. MNK phosphorylates the substrate and converts ATP to ADP, which w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
Go to US Patent

TargetMAP kinase-interacting serine/threonine-protein kinase 2(Human)
Hepagene Therapeutics (Hk

US Patent
LigandPNGBDBM660326(US20240092799, Compound IIb)
Affinity DataIC50: 5.5nMAssay Description:This protocol establishes the binding assays for MNK1 and MNK2 using ADP-Glo assay. MNK phosphorylates the substrate and converts ATP to ADP, which w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
Go to US Patent