BDBM660096 (E)-3-(3-(3-Oxa-8-azabicyclo[3.2.1]octan-8-yl)-3-oxoprop-1-en-1-yl)-N-cyclopropyl-7-hydroxy-4-isobutyl-5-oxo-4,5-dihydropyrazolo[1,5-a]pyrimidine-6-carboxamide::US20240092784, Example 533

SMILES CC(C)Cn1c2c(\C=C\C(=O)N3C4CCC3COC4)cnn2c(O)c(C(=O)NC2CC2)c1=O

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 660096   

TargetSepiapterin reductase(Human)
Nissan Chemical

US Patent
LigandPNGBDBM660096((E)-3-(3-(3-Oxa-8-azabicyclo[3.2.1]octan-8-yl)-3-o...)
Affinity DataIC50: 0.640nMAssay Description:Human SPR inhibitory activity was measured by using a 384-well low adsorption clear plate (Greiner) with buffer D containing 100 mM Tris-HCl (pH 7.5)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
Go to US Patent