BDBM660013 (E)-N6-Cyclopropyl-7-hydroxy-4-isobutyl-3-(3-morpholino-3-oxoprop-1-en-1-yl)-5-oxo-4,5-dihydropyrazolo[1,5-a]pyrimidine-2,6-dicarboxamide::US20240092784, Example 450

SMILES CC(C)Cn1c2c(\C=C\C(=O)N3CCOCC3)c(nn2c(O)c(C(=O)NC2CC2)c1=O)C(N)=O

InChI Key InChIKey=VSUZLTYVSMZIHL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 660013   

TargetSepiapterin reductase(Human)
Nissan Chemical

US Patent
LigandPNGBDBM660013((E)-N6-Cyclopropyl-7-hydroxy-4-isobutyl-3-(3-morph...)
Affinity DataIC50: 0.600nMAssay Description:Human SPR inhibitory activity was measured by using a 384-well low adsorption clear plate (Greiner) with buffer D containing 100 mM Tris-HCl (pH 7.5)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
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