BDBM659964 N-Cyclopropyl-9-hydroxy-6-neopentyl-2,7-dioxo-1,2,4,5,6,7-hexahydropyrimido[1',2':1,5]pyrazolo[3,4-d][1,3]oxazepine-8-carboxamide::US20240092784, Example 401

SMILES CC(C)(C)Cn1c2c3CCOC(=O)Nc3nn2c(O)c(C(=O)NC2CC2)c1=O

InChI Key InChIKey=PDGWIKMQPUGKCR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 659964   

TargetSepiapterin reductase(Human)
Nissan Chemical

US Patent
LigandPNGBDBM659964(N-Cyclopropyl-9-hydroxy-6-neopentyl-2,7-dioxo-1,2,...)
Affinity DataIC50: 0.560nMAssay Description:Human SPR inhibitory activity was measured by using a 384-well low adsorption clear plate (Greiner) with buffer D containing 100 mM Tris-HCl (pH 7.5)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
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