BDBM659949 (E)-N-Cyclopropyl-7-hydroxy-4-((4-methyltetrahydro-2H-pyran-4-yl)methyl)-3-(3-morpholino-3-oxoprop-1-en-1-yl)-5-oxo-4,5-dihydropyrazolo[1,5-a]pyrimidine-6-carboxamide::US20240092784, Example 386

SMILES CC1(Cn2c3c(\C=C\C(=O)N4CCOCC4)cnn3c(O)c(C(=O)NC3CC3)c2=O)CCOCC1

InChI Key InChIKey=QSSZABQPMOSJJP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 659949   

TargetSepiapterin reductase(Human)
Nissan Chemical

US Patent
LigandPNGBDBM659949((E)-N-Cyclopropyl-7-hydroxy-4-((4-methyltetrahydro...)
Affinity DataIC50: 0.600nMAssay Description:Human SPR inhibitory activity was measured by using a 384-well low adsorption clear plate (Greiner) with buffer D containing 100 mM Tris-HCl (pH 7.5)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
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