BDBM659927 (E)-N-Cyclopropyl-4-((1-fluorocyclopropyl)methyl)-7-hydroxy-3-(3-morpholino-3-oxoprop-1-en-1-yl)-5-oxo-4,5-dihydropyrazolo[1,5-a]pyrimidine-6-carboxamide::US20240092784, Example 364

SMILES Oc1c(C(=O)NC2CC2)c(=O)n(CC2(F)CC2)c2c(\C=C\C(=O)N3CCOCC3)cnn12

InChI Key InChIKey=KRVMSOVXAIYRJM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 659927   

TargetSepiapterin reductase(Human)
Nissan Chemical

US Patent
LigandPNGBDBM659927((E)-N-Cyclopropyl-4-((1-fluorocyclopropyl)methyl)-...)
Affinity DataIC50: 0.630nMAssay Description:Human SPR inhibitory activity was measured by using a 384-well low adsorption clear plate (Greiner) with buffer D containing 100 mM Tris-HCl (pH 7.5)...More data for this Ligand-Target Pair
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Date in BDB:
6/4/2024
Entry Details
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