BDBM659822 N-Cyclopropyl-7-hydroxy-4-isobutyl-5-oxo-3-((pyridin-3-yloxy)methyl)-4,5-dihydropyrazolo[1,5-a]pyrimidine-6-carboxamide::US20240092784, Example 259

SMILES CC(C)Cn1c2c(COc3cccnc3)cnn2c(O)c(C(=O)NC2CC2)c1=O

InChI Key InChIKey=LMQZJGNRAXPURQ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 659822   

TargetSepiapterin reductase(Human)
Nissan Chemical

US Patent
LigandPNGBDBM659822(N-Cyclopropyl-7-hydroxy-4-isobutyl-5-oxo-3-((pyrid...)
Affinity DataIC50: 0.180nMAssay Description:Human SPR inhibitory activity was measured by using a 384-well low adsorption clear plate (Greiner) with buffer D containing 100 mM Tris-HCl (pH 7.5)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
Go to US Patent