BDBM659702 (R/S)-3-(4-cyclopropylphenyl)-7-((2-(1-methyl-1H-pyrazol-4-yl)pyridin-4-yl)oxy)-2,3-dihydro-[1,4]dioxino[2,3-b]pyridine::US20240092774, Compound 48

SMILES Cn1cc(cn1)-c1cc(Oc2cnc3O[C@H](COc3c2)c2ccc(cc2)C2CC2)ccn1

InChI Key InChIKey=DQYJZYDKIPKLEC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 659702   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Hutchison Medipharma

US Patent
LigandPNGBDBM659702((R/S)-3-(4-cyclopropylphenyl)-7-((2-(1-methyl-1H-p...)
Affinity DataIC50: 5nMAssay Description:Methods: 1) Kinase Reaction (10 μL System)2.5 μL of 4× test compound was added to each reaction well of the 384 plate, and the correspondin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
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