BDBM659280 US20240092759, Compound 6

SMILES Clc1cccc(c1)-c1cc(cn(-c2cccnc2)c1=O)-c1ccccc1C#N

InChI Key InChIKey=DUXWXGQOMNHTOZ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 659280   

TargetReplicase polyprotein 1a(2019-nCoV)
Yale University

US Patent
LigandPNGBDBM659280(US20240092759, Compound 6)
Affinity DataIC50: 9.99E+3nMAssay Description:Inhibition of proteolytic activity was tested using recombinant SARS-Cov-2 Mpro, as described herein in the Experimental section. For the kinetic ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1a(2019-nCoV)
Yale University

US Patent
LigandPNGBDBM659280(US20240092759, Compound 6)
Affinity DataIC50: 9.99E+3nMAssay Description:Inhibition of proteolytic activity was tested using recombinant SARS-Cov-2 Mpro, as described herein in the Experimental section. For the kinetic ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2024
Entry Details
Go to US Patent

TargetReplicase polyprotein 1ab(2019-nCoV)
Emory University

Curated by ChEMBL
LigandPNGBDBM659280(US20240092759, Compound 6)
Affinity DataIC50: 9.99E+3nMAssay Description:Inhibition of SARS-CoV-2 main protease expressed in Escherichia coli using [NH2-C(EDANS)VNSTQSGLRK(DABCYL)M-COOH] FRET peptide as substrate pre-incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2024
Entry Details
PubMed