BDBM65896 2-benzylsulfonyl-5-chloro-N-(5-ethyl-1,3,4-thiadiazol-2-yl)pyrimidine-4-carboxamide::5-chloranyl-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-2-(phenylmethyl)sulfonyl-pyrimidine-4-carboxamide::5-chloro-N-(5-ethyl-1,3,4-thiadiazol-2-yl)-2-(phenylmethyl)sulfonyl-4-pyrimidinecarboxamide::MLS001116217::SMR000625786::cid_16446678

SMILES CCc1nnc(NC(=O)c2nc(ncc2Cl)S(=O)(=O)Cc2ccccc2)s1

InChI Key InChIKey=KQXGUMFOKFQRCK-UHFFFAOYSA-N

Data  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 65896   

TargetPotassium voltage-gated channel subfamily KQT member 2(Rat)
Johns Hopkins Ion Channel Center

Curated by PubChem BioAssay
LigandPNGBDBM65896(MLS001116217 | 5-chloro-N-(5-ethyl-1,3,4-thiadiazo...)
Affinity DataEC50:  1.73E+4nMAssay Description:BioAssay Type: Confirmatory, Concentration-Response Relationship Observed Source (MLPCN Center Name): Johns Hopkins Ion Channel Center (JHICC) Center...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetBcl-2-like protein 11(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM65896(MLS001116217 | 5-chloro-N-(5-ethyl-1,3,4-thiadiazo...)
Affinity DataEC50:  5.81E+4nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2011
Entry Details
PCBioAssay
TargetHepatocyte nuclear factor 4-alpha(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM65896(MLS001116217 | 5-chloro-N-(5-ethyl-1,3,4-thiadiazo...)
Affinity DataIC50: 5.95E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetPerilipin-1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM65896(MLS001116217 | 5-chloro-N-(5-ethyl-1,3,4-thiadiazo...)
Affinity DataIC50: 4.25E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay
TargetPerilipin-5(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM65896(MLS001116217 | 5-chloro-N-(5-ethyl-1,3,4-thiadiazo...)
Affinity DataIC50: 4.14E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2013
Entry Details
PCBioAssay