BDBM658440 N-(4-((6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl)oxy)bicyclo[2.1.1]hexan-1-yl)acrylamide and N-methyl-N-(4-((6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyrazin-4-yl)oxy)bicyclo[2.1.1]hexan-1-yl)acrylamide::US20240083900, Example 98::US20240083900, Example 99. 100

SMILES CN(C(=O)C=C)C12CC(C1)(CC2)Oc1nc(cn2nccc12)-c1cnn(C)c1

InChI Key InChIKey=ICHAHJBTTZHEEA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 658440   

TargetTyrosine-protein kinase BTK(Human)
Biogen Ma

US Patent
LigandPNGBDBM658440(US20240083900, Example 98 | N-(4-((6-(1-methyl-1H-...)
Affinity DataIC50: 1nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Biogen Ma

US Patent
LigandPNGBDBM658440(US20240083900, Example 98 | N-(4-((6-(1-methyl-1H-...)
Affinity DataIC50: 1nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
Go to US Patent