BDBM658435 1-((1R,5S,6r)-6-(((3-fluoro-6-(1-methyl-1H-pyrazol-4-yl)pyrazolo[1,5-a]pyridin-4-yl)oxy)methyl)-3-azabicyclo[3.1.1]heptan-3-yl)prop-2-en-1-one::US20240083900, Example 84::US20240083900, Example 85

SMILES Cn1cc(cn1)-c1cc(OC[C@@H]2[C@H]3C[C@@H]2CN(C3)C(=O)C=C)c2c(F)cnn2c1

InChI Key InChIKey=JQSHZGMYSPURHT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 658435   

TargetTyrosine-protein kinase BTK(Human)
Biogen Ma

US Patent
LigandPNGBDBM658435(US20240083900, Example 84 | 1-((1R,5S,6r)-6-(((3-f...)
Affinity DataIC50: 1nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
Go to US Patent

TargetTyrosine-protein kinase BTK(Human)
Biogen Ma

US Patent
LigandPNGBDBM658435(US20240083900, Example 84 | 1-((1R,5S,6r)-6-(((3-f...)
Affinity DataIC50: 1nMAssay Description:The purpose of the BTK in vitro assay is to determine compound potency against BTK through the measurement of IC50. Compound inhibition is measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
Go to US Patent