BDBM658054 6-[2,6-difluoro-3-(5-fluoro-2-methoxypyridine-3-sulfonamido)phenyl]-N-methylimidazo[1,5-a]pyridine-1-carboxamide ::US20240083897, Compound 7

SMILES CNC(=O)c1ncn2cc(ccc12)-c1c(F)ccc(NS(=O)(=O)c2cc(F)cnc2OC)c1F

InChI Key InChIKey=IRLYMMZQCUWWRO-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 658054   

TargeteIF-2-alpha kinase GCN2(Human)
Hibercell

US Patent
LigandPNGBDBM658054(US20240083897, Compound 7 | 6-[2,6-difluoro-3-(5-f...)
Affinity DataIC50: 50nMAssay Description:GCN2 protein was obtained from Carna Biosciences (cat #05-153). The protein was diluted in assay buffer (ThermoFisher Scientific, #PV6135), 2 mM dith...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
Go to US Patent

TargeteIF-2-alpha kinase GCN2(Human)
Hibercell

US Patent
LigandPNGBDBM658054(US20240083897, Compound 7 | 6-[2,6-difluoro-3-(5-f...)
Affinity DataIC50: 43nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargeteIF-2-alpha kinase GCN2(Human)
Hibercell

US Patent
LigandPNGBDBM658054(US20240083897, Compound 7 | 6-[2,6-difluoro-3-(5-f...)
Affinity DataEC50:  440nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM658054(US20240083897, Compound 7 | 6-[2,6-difluoro-3-(5-f...)
Affinity DataEC50: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed