BDBM658049 5-chloro-N-[2,4-difluoro-3-[1-(1H-imidazol-2-yl)imidazo[1,5-a]pyridin-6-yl]phenyl]-2-methoxypyridine-3-sulfonamide ::US20240083897, Compound 2

SMILES COc1ncc(Cl)cc1S(=O)(=O)Nc1ccc(F)c(c1F)-c1ccc2c(ncn2c1)-c1ncc[nH]1

InChI Key InChIKey=JVXMCRWYDRLMDG-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 658049   

TargeteIF-2-alpha kinase GCN2(Human)
Hibercell

US Patent
LigandPNGBDBM658049(US20240083897, Compound 2 | 5-chloro-N-[2,4-difluo...)
Affinity DataIC50: 50nMAssay Description:GCN2 protein was obtained from Carna Biosciences (cat #05-153). The protein was diluted in assay buffer (ThermoFisher Scientific, #PV6135), 2 mM dith...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
Go to US Patent

TargeteIF-2-alpha kinase GCN2(Human)
Hibercell

US Patent
LigandPNGBDBM658049(US20240083897, Compound 2 | 5-chloro-N-[2,4-difluo...)
Affinity DataIC50: 2.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargeteIF-2-alpha kinase GCN2(Human)
Hibercell

US Patent
LigandPNGBDBM658049(US20240083897, Compound 2 | 5-chloro-N-[2,4-difluo...)
Affinity DataEC50:  13nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
LigandPNGBDBM658049(US20240083897, Compound 2 | 5-chloro-N-[2,4-difluo...)
Affinity DataEC50:  1.70E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed