BDBM658046 1-(4-Fluoro-2-methylphenyl)-3-(2-methyl-6-oxo-1,6-dihydropyridin-3-yl)-4-oxo-1,2,3,4-tetrahydropyrido[3,4-d]pyrimidine-6-carbonitrile::US20240083896, Example 22

SMILES Cc1cc(F)ccc1N1CN(C(=O)c2cc(ncc12)C#N)c1ccc(=O)[nH]c1C

InChI Key InChIKey=QRIZGIGTBQIIEN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 658046   

TargetSodium channel protein type 5 subunit alpha(Human)
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM658046(US20240083896, Example 22 | 1-(4-Fluoro-2-methylph...)
Affinity DataIC50: 3.98E+3nMAssay Description:Pharmacological assessment of the compounds of the invention was performed using HEK293-Nav1.8 in combination with an assay developed on the QPatch 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
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