BDBM658042 7-chloro-1-(4- fluoro-2-methyl- phenyl)-3-(2-meth- yl-6-oxo-1,6- dihydropyridin- 3-yl)-2,3-dihydro- pyrido[4,3-d]pyrim- idin-4(1H)-one::US20240083896, Example 18

SMILES Cc1cc(F)ccc1N1CN(C(=O)c2cnc(Cl)cc12)c1ccc(=O)[nH]c1C

InChI Key InChIKey=ONKNEMCHFPWKKU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 658042   

TargetSodium channel protein type 5 subunit alpha(Human)
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM658042(US20240083896, Example 18 | 7-chloro-1-(4- fluoro-...)
Affinity DataIC50: 251nMAssay Description:Pharmacological assessment of the compounds of the invention was performed using HEK293-Nav1.8 in combination with an assay developed on the QPatch 4...More data for this Ligand-Target Pair
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Date in BDB:
5/30/2024
Entry Details
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