BDBM658041 1-(3,4-Difluoro-2-methylphenyl)-3-(2-methyl-6-oxo-1,6-dihydropyridin-3-yl)-6-(trifluoromethyl)-2,3-dihydropyrido[3,4-d]pyrimidin-4(1H)-one::US20240083896, Example 17

SMILES Cc1[nH]c(=O)ccc1N1CN(c2ccc(F)c(F)c2C)c2cnc(cc2C1=O)C(F)(F)F

InChI Key InChIKey=IHQIUCIHAHGGQF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 658041   

TargetSodium channel protein type 5 subunit alpha(Human)
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM658041(US20240083896, Example 17 | 1-(3,4-Difluoro-2-meth...)
Affinity DataIC50: 63.1nMAssay Description:Pharmacological assessment of the compounds of the invention was performed using HEK293-Nav1.8 in combination with an assay developed on the QPatch 4...More data for this Ligand-Target Pair
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Date in BDB:
5/30/2024
Entry Details
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