BDBM658029 1-(4-fluoro-2- methylphenyl)-3- (2-methyl-6-oxo- 1,6-dihydropyr- idin-3-yl)-7-(tri- fluoromethyl)- 2,3-dihydropyr- ido[4,3-d]pyrim- idin-4(1H)-one::US20240083896, Example 4

SMILES Cc1cc(F)ccc1N1CN(C(=O)c2cnc(cc12)C(F)(F)F)c1ccc(=O)[nH]c1C

InChI Key InChIKey=DXWPPERIQHGVFI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 658029   

TargetSodium channel protein type 5 subunit alpha(Human)
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM658029(US20240083896, Example 4 | 1-(4-fluoro-2- methylph...)
Affinity DataIC50: 158nMAssay Description:Pharmacological assessment of the compounds of the invention was performed using HEK293-Nav1.8 in combination with an assay developed on the QPatch 4...More data for this Ligand-Target Pair
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Date in BDB:
5/30/2024
Entry Details
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