BDBM658028 6-chloro-1-(4- fluoro-2-isopro- pylphenyl)-3-(2- methyl-6-oxo-1,6- dihydropyridin- 3-yl)-2,3-dihydro- pyrido-[3,4-d]pyr- imidin-4(1H)-one::US20240083896, Example 3

SMILES CC(C)c1cc(F)ccc1N1CN(C(=O)c2cc(Cl)ncc12)c1ccc(=O)[nH]c1C

InChI Key InChIKey=LZHXYPOGLCFHRH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 658028   

TargetSodium channel protein type 5 subunit alpha(Human)
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM658028(US20240083896, Example 3 | 6-chloro-1-(4- fluoro-2...)
Affinity DataIC50: 100nMAssay Description:Pharmacological assessment of the compounds of the invention was performed using HEK293-Nav1.8 in combination with an assay developed on the QPatch 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
Go to US Patent