BDBM658026 1-(4-Fluoro-2-methylphenyl)-3-(2-methyl-6-oxo-1,6-dihydropyridin-3-yl)-7-(trifluoromethyl)-2,3-dihydropyrido[3,2-d]pyrimidin-4(1H)-one::US20240083896, Example 1

SMILES Cc1cc(F)ccc1N1CN(C(=O)c2ncc(cc12)C(F)(F)F)c1ccc(=O)[nH]c1C

InChI Key InChIKey=UHMPFECPUUXOQG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 658026   

TargetSodium channel protein type 5 subunit alpha(Human)
Glaxosmithkline Intellectual Property Development

US Patent
LigandPNGBDBM658026(US20240083896, Example 1 | 1-(4-Fluoro-2-methylphe...)
Affinity DataIC50: 1.26E+3nMAssay Description:Pharmacological assessment of the compounds of the invention was performed using HEK293-Nav1.8 in combination with an assay developed on the QPatch 4...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
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