BDBM657992 (S)-4-Amino-N-(1-cyano-2-(2-(4-fluorophenyl)-1,2,3,4-tetrahydroisoquinolin-6-yl)ethyl)tetrahydro-2H-pyran-4-carboxamide::US20240083888, Compound 57

SMILES NC1(CCOCC1)C(=O)N[C@@H](Cc1ccc2CN(CCc2c1)c1ccc(F)cc1)C#N

InChI Key InChIKey=MZWZXNFFAUCPMB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 657992   

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandPNGBDBM657992((S)-4-Amino-N-(1-cyano-2-(2-(4-fluorophenyl)-1,2,3...)
Affinity DataIC50: 48nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2024
Entry Details
Go to US Patent