BDBM657978 (2S)-N-(1-Cyano-2-(2-fluoro-9-(methylsulfonyl)-6H-benzo[c]chromen-3-yl)ethyl)-1,4-oxazepane-2-carboxamide::US20240083888, Compound 43

SMILES [#6]S(=O)(=O)c1ccc2-[#6]-[#8]-c3cc(-[#6]-[#6](\[#7]=[#6](\c4ccccc4)-c4ccccc4)C#N)c(F)cc3-c2c1

InChI Key InChIKey=FFIGLDJHURSZNZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 657978   

TargetDipeptidyl peptidase 1(Human)
Reistone Biopharma Company

US Patent
LigandPNGBDBM657978((2S)-N-(1-Cyano-2-(2-fluoro-9-(methylsulfonyl)-6H-...)
Affinity DataIC50: 26nMAssay Description:1) Preparation of test compound plate: The test compounds and positive control AZD7986 were dissolved in 100% DMSO to obtain compound stock solutions...More data for this Ligand-Target Pair
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Date in BDB:
5/30/2024
Entry Details
Go to US Patent