BDBM657021 US20240076297, Example 17.4

SMILES COc1cccc2c3nc(nn3c(N)nc12)[C@H](C)CO

InChI Key InChIKey=SAZWDTYBIPOIIM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 657021   

TargetAdenosine receptor A2a(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM657021(US20240076297, Example 17.4)
Affinity DataIC50: 145nMAssay Description:Method (A): 148 μL (5 μg/mL) membranes (Perkin Elmer, Cat. No. RBHA2aM400UA) and 2 μL compounds of the invention to be tested (test co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2024
Entry Details
Go to US Patent

TargetAdenosine receptor A2b(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM657021(US20240076297, Example 17.4)
Affinity DataIC50: 1.07E+3nMAssay Description:Method (B): Binding affinity using SPA was conducted as follows. Test compounds (50 nL) were dispensed into individual wells of a 384-well OptiPlate&...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2024
Entry Details
Go to US Patent