BDBM657016 US20240076297, Example 13.16

SMILES COc1cc2nc(N)n3nc(CCS(=O)(=O)CC(C)C)nc3c2cc1F

InChI Key InChIKey=BHADBXWAMZFXNY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 657016   

TargetAdenosine receptor A2a(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM657016(US20240076297, Example 13.16)
Affinity DataIC50: 107nMAssay Description:Method (A): 148 μL (5 μg/mL) membranes (Perkin Elmer, Cat. No. RBHA2aM400UA) and 2 μL compounds of the invention to be tested (test co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2024
Entry Details
Go to US Patent

TargetAdenosine receptor A2b(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM657016(US20240076297, Example 13.16)
Affinity DataIC50: 1.08E+3nMAssay Description:Method (A): 148 μL (5 μg/mL) membranes (Perkin Elmer, Cat. No. RBHA2aM400UA) and 2 μL compounds of the invention to be tested (test co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2024
Entry Details
Go to US Patent