BDBM656993 US20240076297, Example 5.3A::US20240076297, Example 5.3B

SMILES COc1cccc2c3nc(CCC4CCc5c(C4)nnn5C4CC(F)(F)C4)nn3c(N)nc12

InChI Key InChIKey=COZJGWSCLVNXOA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 656993   

TargetAdenosine receptor A2a(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM656993(US20240076297, Example 5.3B | US20240076297, Examp...)
Affinity DataIC50: 0.900nMAssay Description:Method (A): 148 μL (5 μg/mL) membranes (Perkin Elmer, Cat. No. RBHA2aM400UA) and 2 μL compounds of the invention to be tested (test co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2024
Entry Details
Go to US Patent

TargetAdenosine receptor A2a(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM656993(US20240076297, Example 5.3B | US20240076297, Examp...)
Affinity DataIC50: 0.900nMAssay Description:Method (A): 148 μL (5 μg/mL) membranes (Perkin Elmer, Cat. No. RBHA2aM400UA) and 2 μL compounds of the invention to be tested (test co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2024
Entry Details
Go to US Patent

TargetAdenosine receptor A2b(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM656993(US20240076297, Example 5.3B | US20240076297, Examp...)
Affinity DataIC50: 3.10nMAssay Description:Method (A): 148 μL (5 μg/mL) membranes (Perkin Elmer, Cat. No. RBHA2aM400UA) and 2 μL compounds of the invention to be tested (test co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2024
Entry Details
Go to US Patent