BDBM656586 4-[[(2R,3S,4S,5R)-3-[2-[(3,3-difluorocyclobutyl)methoxy]-3,4-difluoro-phenyl]-4,5-dimethyl-5-(trifluoromethyl)tetrahydrofuran-2-carbonyl]amino]pyridine-2-carboxamide ::US11919887, Compound 146

SMILES COC(=O)c1cc(NC(=O)[C@@H]2O[C@](C)([C@@H](C)[C@H]2c2ccc(F)c(F)c2O)C(F)(F)F)ccn1

InChI Key InChIKey=YCMONYSSUQGVHA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 656586   

TargetSodium channel protein type 5 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM656586(US11919887, Compound 146 | 4-[[(2R,3S,4S,5R)-3-[2-...)
Affinity DataIC50: 55nMAssay Description:Assay Protocol (7 Key Steps):1) To reach the final concentration in each well, 400 nL of each compound was pre-spotted (in neat DMSO) into polypropyl...More data for this Ligand-Target Pair
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Date in BDB:
5/17/2024
Entry Details
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