BDBM656555 US11919887, Compound 87

SMILES COc1c(F)c(F)ccc1[C@H]1C[C@@](C)(O[C@@H]1C(=O)Nc1ccnc(c1)C(N)=O)C(C)(F)F

InChI Key InChIKey=QGPXJRWCPXXASO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 656555   

TargetSodium channel protein type 5 subunit alpha(Human)
Vertex Pharmaceuticals

US Patent
LigandPNGBDBM656555(US11919887, Compound 87)
Affinity DataIC50: 550nMAssay Description:Assay Protocol (7 Key Steps):1) To reach the final concentration in each well, 400 nL of each compound was pre-spotted (in neat DMSO) into polypropyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2024
Entry Details
US Patent