BDBM656069 US20240067645, Example 31

SMILES Cn1c2cc(Cl)cnc2n(C2CCN(Cc3ccc(OC(F)(F)F)cc3)CC2(C)C)c(=O)c1=O

InChI Key InChIKey=PJBWNDGLDPLYHK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 656069   

TargetDiacylglycerol kinase alpha(Human)
Lg Chem

US Patent
LigandPNGBDBM656069(US20240067645, Example 31)
Affinity DataIC50: 2.65E+3nMAssay Description:First, 3×OAG (3 mM)/ATP (0.45 mM) substrate solution was prepared from 1× substrate assay buffer (40 mM MOPS (pH 7.2), 20 mM MgCl2, 1 mM DTT, 0.4 mM ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
Go to US Patent