BDBM655989 2-((1R,5S,6R)-3-(7,7-difluoro-2-((S)-2-(methyl-d3)azetidin-1-yl)-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)-3-azabicyclo[3.1.1]heptan-6-yl)acetic acid ::US20240067633, Compound 16

SMILES C[C@H]1CCN1c1nc2c(CCC2(F)F)c(n1)N1C[C@@H]2C[C@H](C1)C2CC(O)=O

InChI Key InChIKey=QUIFFYWMCXCBTH-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 655989   

TargetKetohexokinase(Human)
Sichuan Haisco Pharmaceutical Co.

US Patent
LigandPNGBDBM655989(2-((1R,5S,6R)-3-(7,7-difluoro-2-((S)-2-(methyl-d3)...)
Affinity DataEC50:  37.7nMAssay Description:Experiment of Inhibitory Activity Against KHK In Vitro: With the involvement of ATP, fructokinase phosphorylates fructose to produce fructose-1-phosp...More data for this Ligand-Target Pair
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Date in BDB:
5/10/2024
Entry Details
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