BDBM655988 US20240067633, Isomer 1 of compound 8

SMILES C[C@H]1CCN1c1nc(N2CC[C@@H](CC(O)=O)C2)c2CCC(F)(F)c2c1C#N

InChI Key InChIKey=IYCWRODKVCOCPW-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 655988   

TargetKetohexokinase(Human)
Sichuan Haisco Pharmaceutical Co.

US Patent
LigandPNGBDBM655988(US20240067633, Isomer 1 of compound 8)
Affinity DataEC50:  58.6nMAssay Description:Experiment of Inhibitory Activity Against KHK In Vitro: With the involvement of ATP, fructokinase phosphorylates fructose to produce fructose-1-phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
Go to US Patent

TargetKetohexokinase Isoform A(Human)
Sichuan Haisco Pharmaceutical Co.

US Patent
LigandPNGBDBM655988(US20240067633, Isomer 1 of compound 8)
Affinity DataEC50:  59.7nMAssay Description:Experiment of Inhibitory Activity Against KHK In Vitro: With the involvement of ATP, fructokinase phosphorylates fructose to produce fructose-1-phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
Go to US Patent