BDBM655987 (S)-2-(1-(4-cyano-5,5-difluoro-3-(2-methylazetidin-1-yl)-6,7-dihydro-5H-cyclopenta[c]pyridin-1-yl)azetidin-3-yl)acetic acid ::US20240067633, Compound 7

SMILES C[C@H]1CCN1c1nc(N2CC(CC(O)=O)C2)c2CCC(F)(F)c2c1C#N

InChI Key InChIKey=WGIHVFWBGGOLPZ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 655987   

TargetKetohexokinase(Human)
Sichuan Haisco Pharmaceutical Co.

US Patent
LigandPNGBDBM655987((S)-2-(1-(4-cyano-5,5-difluoro-3-(2-methylazetidin...)
Affinity DataEC50:  36.5nMAssay Description:Experiment of Inhibitory Activity Against KHK In Vitro: With the involvement of ATP, fructokinase phosphorylates fructose to produce fructose-1-phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
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TargetKetohexokinase Isoform A(Human)
Sichuan Haisco Pharmaceutical Co.

US Patent
LigandPNGBDBM655987((S)-2-(1-(4-cyano-5,5-difluoro-3-(2-methylazetidin...)
Affinity DataEC50:  35.2nMAssay Description:Experiment of Inhibitory Activity Against KHK In Vitro: With the involvement of ATP, fructokinase phosphorylates fructose to produce fructose-1-phosp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/10/2024
Entry Details
Go to US Patent