BDBM6558 3-quinolinecarbonitrile deriv. 26::4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[(E)-2-(pyridin-3-yl)ethenyl]quinoline-3-carbonitrile

SMILES COc1cc(Nc2c(cnc3cc(\C=C\c4cccnc4)c(OC)cc23)C#N)c(Cl)cc1Cl

InChI Key InChIKey=ODNSWRUGVHZZIW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 6558   

LigandPNGBDBM6558(4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50: 8.40nMpH: 7.5 T: 2°CAssay Description:Kinase assays were performed using the europium/APC detection format (LANCE, Perkin Elmer). HTRF is based on the proximity of europium cryptate (dono...More data for this Ligand-Target Pair
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Date in BDB:
11/15/2005
Entry Details Article
PubMed