BDBM65547 phenylglycine containing lead compound (4h)

SMILES CC(C)(C)OC(=O)NC(C(=O)Nc1ccc(cc1)C(=O)NO)c1ccccc1

InChI Key InChIKey=HZCLSSBYCNNVNM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 65547   

TargetHistone deacetylase 8(Human)
Qingdao University

LigandPNGBDBM65547(phenylglycine containing lead compound (4h))
Affinity DataIC50: 1.52E+3nMAssay Description:The nucleus extract was extracted from HDAC8 enzyme was expressed in Escherichia coli. Boc-Lys (acetyl)-AMC was used as the substrate of HDAC. SAHA w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details Article
PubMed