BDBM655201 US11912703, Example 317::US11912703, Example 342

SMILES COc1cc(cn2ncnc12)-c1[nH]c2cnc(cc2c1C(C)C)C1CCC(CC1)NC1CCOC1

InChI Key InChIKey=GCZWXNIIAYIDAG-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 655201   

TargetToll-like receptor 7(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM655201(US11912703, Example 342 | US11912703, Example 317)
Affinity DataIC50: 2.10nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
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TargetToll-like receptor 8(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM655201(US11912703, Example 342 | US11912703, Example 317)
Affinity DataIC50: 7.10nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
Go to US Patent

TargetToll-like receptor 9(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM655201(US11912703, Example 342 | US11912703, Example 317)
Affinity DataIC50: 34nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
Go to US Patent

TargetToll-like receptor 7(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM655201(US11912703, Example 342 | US11912703, Example 317)
Affinity DataIC50: 3.80nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
Go to US Patent

TargetToll-like receptor 8(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM655201(US11912703, Example 342 | US11912703, Example 317)
Affinity DataIC50: 8.30nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
Go to US Patent

TargetToll-like receptor 9(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM655201(US11912703, Example 342 | US11912703, Example 317)
Affinity DataIC50: 224nMAssay Description:HEK-Blue-cells (Invivogen) overexpressing human TLR7, TLR8 or TLR9 receptors were used for screening inhibitors of these receptors using an inducible...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
Go to US Patent