BDBM653689 US11911372, Example 112::US20240277683, Example 112

SMILES COCc1ccc(OC)c(c1)-c1cc(NS(=O)(=O)Cc2ccccc2)no1

InChI Key InChIKey=ZLDKOSPPJWIDHY-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 653689   

TargetHistone acetyltransferase KAT6A [507-778](Human)
CTXT PTY LTD

US Patent
LigandPNGBDBM653689(US11911372, Example 112 | US20240277683, Example 1...)
Affinity DataIC50: 171nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

TargetHistone acetyltransferase KAT7(Human)
CTXT PTY LTD

US Patent
LigandPNGBDBM653689(US11911372, Example 112 | US20240277683, Example 1...)
Affinity DataIC50: 1.40E+3nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

TargetHistone acetyltransferase KAT5(Human)
CTXT PTY LTD

US Patent
LigandPNGBDBM653689(US11911372, Example 112 | US20240277683, Example 1...)
Affinity DataIC50: 1.44E+4nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

TargetHistone acetyltransferase KAT5(Human)
CTXT PTY LTD

US Patent
LigandPNGBDBM653689(US11911372, Example 112 | US20240277683, Example 1...)
Affinity DataIC50: 1.44E+4nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
Go to US Patent

TargetHistone acetyltransferase KAT6A [507-778](Human)
CTXT PTY LTD

US Patent
LigandPNGBDBM653689(US11911372, Example 112 | US20240277683, Example 1...)
Affinity DataIC50: 171nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
Go to US Patent

TargetHistone acetyltransferase KAT7(Human)
CTXT PTY LTD

US Patent
LigandPNGBDBM653689(US11911372, Example 112 | US20240277683, Example 1...)
Affinity DataIC50: 1.40E+3nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
Go to US Patent