BDBM653662 US11911372, Example 84

SMILES COc1ccc(cc1-c1cc(NS(=O)(=O)c2c(OC)cccc2OC)no1)-c1ccccc1

InChI Key InChIKey=JVJTVBQZICFIPQ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 653662   

TargetHistone acetyltransferase KAT8 [177-447](Human)
CTXT PTY

US Patent
LigandPNGBDBM653662(US11911372, Example 84)
Affinity DataIC50: 5.51E+3nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
Go to US Patent

TargetHistone acetyltransferase KAT6B [431-2073](Human)
CTXT PTY

US Patent
LigandPNGBDBM653662(US11911372, Example 84)
Affinity DataIC50: 1.55E+3nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
Go to US Patent

LigandPNGBDBM653662(US11911372, Example 84)
Affinity DataIC50: 1.84E+3nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
Go to US Patent

TargetHistone acetyltransferase KAT6A [507-778](Human)
CTXT PTY

US Patent
LigandPNGBDBM653662(US11911372, Example 84)
Affinity DataIC50: 236nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
Go to US Patent

TargetHistone acetyltransferase KAT7 [325-611](Human)
CTXT PTY

US Patent
LigandPNGBDBM653662(US11911372, Example 84)
Affinity DataIC50: 329nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
Go to US Patent