BDBM65361 MLS000714362::N-[(8-hydroxy-7-quinolinyl)-thiophen-2-ylmethyl]propanamide::N-[(8-hydroxy-7-quinolyl)-(2-thienyl)methyl]propionamide::N-[(8-hydroxyquinolin-7-yl)-thiophen-2-ylmethyl]propanamide::N-[(8-oxidanylquinolin-7-yl)-thiophen-2-yl-methyl]propanamide::SMR000274342::cid_3136123

SMILES CCC(=O)NC(c1cccs1)c1ccc2cccnc2c1O

InChI Key InChIKey=LKWVVCSJBMZGAM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 65361   

TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM65361(SMR000274342 | MLS000714362 | cid_3136123 | N-[(8-...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human platelet-type N-terminally His6-tagged 12-lipoxygenase assessed as conjugated diene product formation using arachidonic acid by U...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM65361(SMR000274342 | MLS000714362 | cid_3136123 | N-[(8-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human 5-lipoxygenase assessed as conjugated diene product formation using arachidonic acid by UV-vis spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM65361(SMR000274342 | MLS000714362 | cid_3136123 | N-[(8-...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human reticulocyte N-terminally His6-tagged 15-lipoxygenase-1 assessed as conjugated diene product formation using arachidonic acid by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Human)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM65361(SMR000274342 | MLS000714362 | cid_3136123 | N-[(8-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human reticulocyte N-terminally His6-tagged 15-lipoxygenase-2 assessed as conjugated diene product formation using arachidonic acid by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed