BDBM653587 US11911372, Example 8::US20240277683, Example 8

SMILES COc1ccc(cc1-c1cc(NS(=O)(=O)c2c(OC)cccc2OC)no1)C1CC1

InChI Key InChIKey=RZLILTXFGHTKKM-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 653587   

TargetHistone acetyltransferase KAT7(Human)
CTXT PTY LTD

US Patent
LigandPNGBDBM653587(US11911372, Example 8 | US20240277683, Example 8)
Affinity DataIC50: 102nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

TargetHistone acetyltransferase KAT8(Human)
CTXT PTY LTD

US Patent
LigandPNGBDBM653587(US11911372, Example 8 | US20240277683, Example 8)
Affinity DataIC50: 4.03E+3nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

TargetHistone acetyltransferase KAT5(Human)
CTXT PTY LTD

US Patent
LigandPNGBDBM653587(US11911372, Example 8 | US20240277683, Example 8)
Affinity DataIC50: 416nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

TargetHistone acetyltransferase KAT6A [507-778](Human)
CTXT PTY LTD

US Patent
LigandPNGBDBM653587(US11911372, Example 8 | US20240277683, Example 8)
Affinity DataIC50: 25.2nMAssay Description:o determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 uL in 384-well low volume ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/26/2024
Entry Details
Go to US Patent

TargetHistone acetyltransferase KAT8(Human)
CTXT PTY LTD

US Patent
LigandPNGBDBM653587(US11911372, Example 8 | US20240277683, Example 8)
Affinity DataIC50: 4.03E+3nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
Go to US Patent

TargetHistone acetyltransferase KAT5(Human)
CTXT PTY LTD

US Patent
LigandPNGBDBM653587(US11911372, Example 8 | US20240277683, Example 8)
Affinity DataIC50: 416nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
Go to US Patent

TargetHistone acetyltransferase KAT6A [507-778](Human)
CTXT PTY LTD

US Patent
LigandPNGBDBM653587(US11911372, Example 8 | US20240277683, Example 8)
Affinity DataIC50: 25.2nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
Go to US Patent

TargetHistone acetyltransferase KAT7(Human)
CTXT PTY LTD

US Patent
LigandPNGBDBM653587(US11911372, Example 8 | US20240277683, Example 8)
Affinity DataIC50: 102nMAssay Description:To determine the inhibition of KAT enzymatic activity by test compounds, assay reactions were conducted in a volume of 8 μL in 384-well low volu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2024
Entry Details
Go to US Patent