BDBM653574 7-(2,6-dioxopiperidin-3-yl)-2- (hydroxymethyl)-2,3-dihydro- 6H-[1,4]dioxino[2,3-f]isoindole- 6,8(7H)-dione::US20240059711, Compound B15

SMILES OCC1COc2cc3C(=O)N(C4CCC(=O)NC4=O)C(=O)c3cc2O1

InChI Key InChIKey=GVDXGWNCRQPKIT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 653574   

TargetProtein cereblon(Human)
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US Patent
LigandPNGBDBM653574(7-(2,6-dioxopiperidin-3-yl)-2- (hydroxymethyl)-2,3...)
Affinity DataIC50: 7.89E+3nMAssay Description:The binding to cereblon (CRBN) was determined using the Cereblon Binding Kit (Cisbio, #64BDCRBNPEG) following the manufacturer's instruction. Bri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
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