BDBM653573 (2S)-2-((benzyloxy)methyl)-7- (2,6-dioxopiperidin-3-yl)-2,3- dihydro-6H-[1,4]dioxino[2,3- f]isoindole-6,8(7H)-dione::US20240059711, Compound B14

SMILES Fc1c2C(=O)N(C3CCC(=O)NC3=O)C(=O)c2cc2O[C@@H](COCc3ccccc3)COc12

InChI Key InChIKey=YITJRIJTTQLZLS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 653573   

TargetProtein cereblon(Human)
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US Patent
LigandPNGBDBM653573((2S)-2-((benzyloxy)methyl)-7- (2,6-dioxopiperidin-...)
Affinity DataIC50: 5.16E+3nMAssay Description:The binding to cereblon (CRBN) was determined using the Cereblon Binding Kit (Cisbio, #64BDCRBNPEG) following the manufacturer's instruction. Bri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
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