BDBM653568 (S)-3-(2-((benzyloxy)methyl)-7- oxo-2,3,7,9-tetrahydro-8H- [1,4]dioxino[2,3-e]isoindol-8- yl)-3lambda3-piperidine-2,6-dione::US20240059711, Compound B9

SMILES O=C1N(Cc2c1ccc1OC[C@H](COCc3ccccc3)Oc21)C1CCC(=O)NC1=O

InChI Key InChIKey=JBDLBQPKMKXMOK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 653568   

TargetProtein cereblon(Human)
Regents Of The University Of Michigan

US Patent
LigandPNGBDBM653568((S)-3-(2-((benzyloxy)methyl)-7- oxo-2,3,7,9-tetrah...)
Affinity DataIC50: 580nMAssay Description:The binding to cereblon (CRBN) was determined using the Cereblon Binding Kit (Cisbio, #64BDCRBNPEG) following the manufacturer's instruction. Bri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
Go to US Patent