BDBM653565 (S)-3-((S)-2-(hydroxymethyl)-7- oxo-2,3,7,9-tetrahydro-8H- [1,4]dioxino[2,3-e]isoindol-8- yl)piperidine-2,6-dione::US20240059711, Compound B6

SMILES OC[C@H]1COc2ccc3C(=O)N(Cc3c2O1)[C@H]1CCC(=O)NC1=O

InChI Key InChIKey=XCCLTTWHVFIRLE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 653565   

TargetProtein cereblon(Human)
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US Patent
LigandPNGBDBM653565((S)-3-((S)-2-(hydroxymethyl)-7- oxo-2,3,7,9-tetrah...)
Affinity DataIC50: 540nMAssay Description:The binding to cereblon (CRBN) was determined using the Cereblon Binding Kit (Cisbio, #64BDCRBNPEG) following the manufacturer's instruction. Bri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
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