BDBM653564 3-((S)-3-((benzyloxy)methyl)-7- oxo-3,4,7,9-tetrahydro- [1,4]oxazino[2,3-e]isoindol- 8(2H)-yl)piperidine-2,6-dione::US20240059711, Compound B5

SMILES O=C1N(Cc2c1ccc1N[C@@H](COCc3ccccc3)COc21)C1CCC(=O)NC1=O

InChI Key InChIKey=OMRUBUWRPRLQGY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 653564   

TargetProtein cereblon(Human)
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US Patent
LigandPNGBDBM653564(3-((S)-3-((benzyloxy)methyl)-7- oxo-3,4,7,9-tetrah...)
Affinity DataIC50: 120nMAssay Description:The binding to cereblon (CRBN) was determined using the Cereblon Binding Kit (Cisbio, #64BDCRBNPEG) following the manufacturer's instruction. Bri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
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