BDBM653560 (S)-3-((S)-3- ((benzyloxy)methyl)-7-oxo- 2,3,7,9-tetrahydro-8H- [1,4]dioxino[2,3-e]isoindol-8- yl)piperidine-2,6-dione::US20240059711, Compound B1

SMILES O=C1N(Cc2c1ccc1O[C@H](COCc3ccccc3)COc21)[C@H]1CCC(=O)NC1=O

InChI Key InChIKey=PXUKNRPBJRKSGE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 653560   

TargetProtein cereblon(Human)
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US Patent
LigandPNGBDBM653560((S)-3-((S)-3- ((benzyloxy)methyl)-7-oxo- 2,3,7,9-t...)
Affinity DataIC50: 300nMAssay Description:The binding to cereblon (CRBN) was determined using the Cereblon Binding Kit (Cisbio, #64BDCRBNPEG) following the manufacturer's instruction. Bri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
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