BDBM653371 (P)-1-(6-(4-(6-hydroxy-1- naphthalenyl)-3-methyl- 7-(2-propanyl)-5,6,7,8- tetrahydro-1,7- naphthyridin-2-yl)-2,6- diazaspiro[3.4]octan-2- yl)-2-propane-1-one::US20240059703, Example 18-4

SMILES CC(C)N1CCc2c(C1)nc(N1CCC3(CN(C3)C(=O)C=C)C1)c(C)c2-c1cccc2cc(O)ccc12

InChI Key InChIKey=BBLRGJBMVQWLTB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 653371   

LigandPNGBDBM653371(US20240059703, Example 18-4 | (P)-1-(6-(4-(6-hydro...)
Affinity DataIC50: 17nMAssay Description:Purified GDP-bound KRAS protein (aa 1-169), containing both G12C and C118A amino acid substitutions and an N-terminal His-tag, was pre-incubated in a...More data for this Ligand-Target Pair
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Date in BDB:
4/24/2024
Entry Details
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