BDBM652417 US20240059682, Example 24

SMILES COc1nc2ccc(Oc3c(Cl)cc(NC(=O)c4noc(=O)[nH]4)cc3Cl)cc2n1C1(CC1)C(F)(F)F

InChI Key InChIKey=ZIPANQNBJYCDHO-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 652417   

TargetRetinoic acid receptor RXR-alpha/Thyroid hormone receptor beta(Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM652417(US20240059682, Example 24)
Affinity DataEC50:  480nMAssay Description:Test compounds were prepared as 10 mM DMSO stock solutions. The stock solution (45 uL) was transferred to a 384-well assay plate, and 3-fold, 10-poin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
Go to US Patent

TargetRetinoic acid receptor RXR-alpha/Thyroid hormone receptor alpha(Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM652417(US20240059682, Example 24)
Affinity DataEC50:  3.23E+3nMAssay Description:Test compounds were prepared as 10 mM DMSO stock solutions. The stock solution (45 uL) was transferred to a 384-well assay plate, and 3-fold, 10-poin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
Go to US Patent