BDBM652413 US20240059682, Example 20

SMILES FC(F)c1nc2ccc(Oc3c(Cl)cc(cc3Cl)-n3nc(C#N)c(=O)[nH]c3=O)cc2n1C1CC1

InChI Key InChIKey=KQHWPMUHHZLUGQ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 652413   

TargetRetinoic acid receptor RXR-alpha/Thyroid hormone receptor beta(Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM652413(US20240059682, Example 20)
Affinity DataEC50:  320nMAssay Description:Test compounds were prepared as 10 mM DMSO stock solutions. The stock solution (45 uL) was transferred to a 384-well assay plate, and 3-fold, 10-poin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
Go to US Patent

TargetRetinoic acid receptor RXR-alpha/Thyroid hormone receptor alpha(Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM652413(US20240059682, Example 20)
Affinity DataEC50:  760nMAssay Description:Test compounds were prepared as 10 mM DMSO stock solutions. The stock solution (45 uL) was transferred to a 384-well assay plate, and 3-fold, 10-poin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
Go to US Patent