BDBM652390 2-(3,5-dichloro-4-((3-cyclopropyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5-yl)oxy)phenyl)-3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazine-6-carbonitrile::US20240059682, Example 8

SMILES Clc1cc(cc(Cl)c1Oc1ccc2[nH]c(=O)n(C3CC3)c2c1)-n1nc(C#N)c(=O)[nH]c1=O

InChI Key InChIKey=GZJOPVRARSRMMC-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 652390   

TargetRetinoic acid receptor RXR-alpha/Thyroid hormone receptor beta(Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM652390(US20240059682, Example 8 | 2-(3,5-dichloro-4-((3-c...)
Affinity DataEC50:  330nMAssay Description:Test compounds were prepared as 10 mM DMSO stock solutions. The stock solution (45 uL) was transferred to a 384-well assay plate, and 3-fold, 10-poin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
Go to US Patent

TargetRetinoic acid receptor RXR-alpha/Thyroid hormone receptor alpha(Human)
Terns Pharmaceuticals

US Patent
LigandPNGBDBM652390(US20240059682, Example 8 | 2-(3,5-dichloro-4-((3-c...)
Affinity DataEC50:  3.20E+3nMAssay Description:Test compounds were prepared as 10 mM DMSO stock solutions. The stock solution (45 uL) was transferred to a 384-well assay plate, and 3-fold, 10-poin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2024
Entry Details
Go to US Patent