BDBM652209 (S)-4-(cyclopropyl((5- methylthiophen-3-yl)methyl) carbamoyl)-1- (diphenylcarbamoyl) piperazine-2-carboxylic acid::US11905274, Compound C146::US11905274, Compound C153

SMILES Cc1cc(CN(C2CC2)C(=O)N2CCN([C@@H](C2)C(O)=O)C(=O)N(c2ccccc2)c2ccccc2)cs1

InChI Key InChIKey=DPBXTUDLDKXUBR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 652209   

TargetType-2 angiotensin II receptor(Human)
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM652209((S)-4-(cyclopropyl((5- methylthiophen-3-yl)methyl)...)
Affinity DataIC50: 14.2nMAssay Description:Through the following steps, the inhibitory activity of the compound on AT1R/AT2R (IC50 value) was determined: 1) An appropriate amount of 1 TLB (Tag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
Go to US Patent

TargetType-2 angiotensin II receptor(Human)
Beijing Tide Pharmaceutical

US Patent
LigandPNGBDBM652209((S)-4-(cyclopropyl((5- methylthiophen-3-yl)methyl)...)
Affinity DataIC50: 5.47nMAssay Description:Through the following steps, the inhibitory activity of the compound on AT1R/AT2R (IC50 value) was determined: 1) An appropriate amount of 1 TLB (Tag...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
Go to US Patent